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PORPHYRIA FACTS: PSYCHIATRIC - MENTAL CHANGE
Patients are often dismissed for years as "mentally ill" or "drug seeking."
Some research data indicate that 1 in 300 patients in psychiatric wards have
porphyria.
Data regarding the misdiagnosis of porphyria among the psychiatric population
has rarely been published in medical journals and remains relatively unknown
by the majority of practicing physicians.
SOURCE:
The Porphyrias
The Challenge of Diagnosis
United Health Services
1996
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What is the direct cause of mental changes in acute porphyria patients?
The high level of porphyrins in the heme pathway is responsible for changes in
the CNS 9central nervous system) which causes mental changes to occur.
SOURCE:
Painful porphyrins
Julie L. McDowell
Diseases and disorders
American Chemical Society
2001
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Does porphyria sometimes only present with mental changes?
Porphyria is important in psychiatry as it may present with only psychiatric
symptoms; it may masquerade as a psychosis and the patient may be treated as
a schizophrenic person for years; the only manifestation may be histrionic
personality disorder which may not receive much attention.
SOURCE:
Psychotherapy Psychosomanics
1995;64(3-4):121-30
Porphyria: reexamination of psychiatric implications.
Burgovne K, Swartz R, Ananth J.
Harbor-UCLA Medical Center, Torrance 90509
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Acute intermittent porphyria mimics a variety of commonly occurring disorders.
The mental changes are especially hard to distinguish from the common
psychiatric diseases that porphyria manifestations may portray.
SOURCE:
Robert Johnson MD
Internal Medicine
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Does mental change occur in AIP?
Many somatic diseases such as acute intermittent porphyria
(AIP) are followed by psychiatric and neurological symptoms."
SOURCE:
Vojnosanit Pregl
2001 Jan-Feb;58(1):95-9
Acute intermittent porphyria as
a problem in differential diagnosis
Preradovic M, et. al.
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Is it common for AIP toexperience mental changeduring acute attacks?
AIP patients may have central nervous system signs consisting of mental status
changes,
SOURCE:
Medicine Journal
February 22 2002
Volume 3, Number 2
"Acute intermittent porphyria"
Thomas G DeLoughery, MD
Associate Professor
Department of Medicine
Division of Hematology and Medical Oncology
Oregon Health Sciences University
Portland, Oregon
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Are mental changes a part of HCP?
Confusion and mental changes resembling an acute psychosis may be present
during acute attacks in HCP patients but resolve with remission.
SOURCE:
The Porphyrias
Alana Adams RPH
Welsh Drug Information Center
Cardiff, Wales, U.K.
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