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PORPHYRIA FACTS: NUTRITION - B VITAMINS
VITAMIN B 6 PYRIDOXINE
What are the B Vitamins?
The B Vitamins include thiamine, riboflavin, niacin, pantothenic acid, biotin,
vitamin B6, B-12 and folate (or folic aicd).
SOURCE:
Building Blocks
Sox vitamins you must have
John McIntosh
Nutrition Report
Remedy Winter 2002
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What does B6 do in regards to porphyria?
Pyridoxine [B6] acts as a cofactor in porphyrin biosynthesis.
The human requirement has not been definitely established.
It is however a matter of record that those not receiving enough develop
convulsive seizures.
It is also know that women using oral contraceptives need more of the vitamin."
SOURCE:
Vitamins
Joseph J. Vitale Sr. M.D.
Boston University School of Medicine
Director, Mallory Institute of Pathology, Boston
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What does Vitamin B-6 do?
Vitamin B6 plays a role in the synthesis of antibodies by the immune system,
which are needed to fight many diseases.
It helps maintain normal nerve function and also acts in the formation of red
blood cells.
Vitamin B6 is also required for the chemical reactions needed to digest proteins.
The higher the protein intake, the more the need for vitamin B6.
SOURCE:
Steven Angelo, M.D.
Assistant Professor of Medicine
Yale School of Medicine
New Haven, CT.
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What is another name for Vitamin B-6?
Pyridoxine is another name for Vitamin B-6.
SOURCE:
Steven Angelo, M.D.
Assistant Professor of Medicine
Yale School of Medicine
New Haven, CT.
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What foods are high in B Vitamins?
Poultry, liver, and grains are high in the B Vitamins.
SOURCE:
Vitamins and Minerals:
Healthy Diet & Safe Supplementation
Denise Mortimore
Element
2001
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In what foods is Vitamin B6 found?
Vitamin B6 is found in fortified cereals, beans, meat, fish, poultry, and some
fruits and vegetables.
SOURCE:
John McIntosh
Nutrition Report
Remedy Winter 2002
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What are good sources of Vitamin B-6?
Vitamin B6 is found in beans, nuts, legumes, eggs, meats, fish, whole grains,
and fortified breads and cereals.
SOURCE:
Steven Angelo, M.D.
Assistant Professor of Medicine
Yale School of Medicine
New Haven, CT.
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Vitamin B6 helps form red blood cells and maintain normal brain function.
SOURCE:
John McIntosh
Nutrition Report
Remedy Winter 2002
+++++++++++++++++++++++
Vitamin B6 also helps the body resist disease.
SOURCE:
John McIntosh
Nutrition Report
Remedy Winter 2002
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The body needs Vitamin B6 to use protein and maintain healthy red blood cells.
SOURCE:
Robert Johnson M.D.
Internal Medicine
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As a person consumes more protein, the more B6 a persons needs to consume.
SOURCE:
Althea Wilson MSN RD
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Using proper nutrition in the preparation of daily food intake should supplies all
the recommended daily allowance of Vitamin B6.
SOURCE:
Sheryl Wilson [HCP] MSN RD
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Does a normal diet provide enough Vitamin B6?
The average diet supplies adequate quantities of vitamin B6.
SOURCE:
Steven Angelo, M.D.
Assistant Professor of Medicine
Yale School of Medicine
New Haven, CT.
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How does one know if they have a defiency of Vitamin B6?
Epigastric distress with anorexia and constipation Irritability
Numbness and tingling of hands and feet Postural hypotension
SOURCE:
Good Health Oractices with Vitamin Supplementation
WM. Cornell, et. al.
1995
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Can too much Vitamin B-6cause problems?
Large doses of vitamin B6 can cause neurological disorders and numbness.
Deficiency of this vitamin can cause mouth and tongue sores, irritability,
confusion, and
depression.
(Vitamin B6 deficiency is not common in the United States.)
SOURCE:
Steven Angelo, M.D.
Assistant Professor of Medicine
Yale School of Medicine
New Haven, CT.
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Can experimental Vitamin B6 use lead totoxicity in the body?
Porphyria patients in growing numbers have reportedly been experimenting with
the use of vitamin B6 or the p5p regimen.
It has long been known the the ingestion of megadoses (2 to 6 g/day for 2 to 40
mo) of pyridoxine, may cause progressive sensory ataxia.
In addition it can cause profound lower limb impairment of position and vibration
sense.
With extra doses of pyridoxine the senses of touch, temperature, and pain are
less affected.
SOURCE:
Jeff Danniels, PhD.
Molecular Biology & Alternative Medicine
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What is the RDA for Vitamin B6?
The recommended daily allowance for vitamin B6 in women 19-50 years of age
is 1.3 mg.
In women over 51 years of age the RDA for vitamin B6 is 1.5 mg daily.
In men 19-50 it is 1.3 mg and in those over 51 it is 1.7 mg.
SOURCE:
John McIntosh
Nutrition Report
Remedy Winter 2002
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VITAMIN B “5” - PANTHOTHENIC ACID
What is Vitamin B5?
Vitamin B5 is also known as pantothenic acid or pantothenate.
SOURCE:
Good Health Oractices with Vitamin Supplementation
WM. Cornell, et. al.
1995
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What are the non-therapeutic importances of Vitamin B5?
As part of coenzyme A and other derivatives, pantothenic acid participates in
energy release from protein, carbohydrate, and fat; required in the biosynthesis
of fatty acids.
SOURCE:
Good Health Oractices with Vitamin Supplementation
WM. Cornell, et. al.
1995
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What benefits may be gained by the use of added Vitamin B5?
CONSULT WITH A HEALTH PROFESSIONAL FIRST:
Vitamin B5 supplementation may prevent, correct deficiencies caused by, or be
helpful with, the following conditions:
Acne
Aging
Allergies (allergic rhinitis, hay fever)
Chronic Fatigue Syndrome (CFS, CFIDS)
Constipation
Headache (migraine)
Hypercholesterolemia (high cholesterol) - pantethine
Immunodepression (immune function)
Infection (colds, flu, etc.)
Osteoarthritis
Rheumatoid Arthritis
Sinusitis (sinus infection)
SOURCE:
Good Health Oractices with Vitamin Supplementation
WM. Cornell, et. al.
1995
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What are the Major Sources of Vitamin B5?
Vitamin B5 is present in all plant and animal foods; eggs, kidney, liver, salmon,
and yeast are best sources; possibly synthesized by intestinal bacteria.
SOURCE:
Good Health Oractices with Vitamin Supplementation
WM. Cornell, et. al.
1995
+++++++++++++++++++++++++++
What is the common dosage for Vitamin B5 in adults?
RDA or alI for adults for Vitamin B5 is 5 mg.
An Adult Maintenance - Therapeutic Range is that of 50 - 1,000 mg.
SOURCE:
Good Health Oractices with Vitamin Supplementation
WM. Cornell, et. al.
1995
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What is a niacin or p5p deficiency?
It has been shown that Niacin in relation to p5p is that in a p5p deficiency,
tryptophan metabolism is impaired.
When tryptophan metabolism is impaired, this willprogress to the point that
niacin is no longer beingmanufactured by the body.
When this takes place there is a Niacin deficiency.
SOURCE:
The real truth about vitamins and antioxidants.
DeCava, J. A.
(1997).
Centerville, Massachusetts,
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What are the non-therapeutic importances of Vitamin B5?
As part of coenzyme A and other derivatives, pantothenic acid participates in
energy release from protein, carbohydrate, and fat; required in the biosynthesis
of fatty acids. ‘
SOURCE:
Beth Ann Kaiser
MSN Nutritional Health
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VITAMIN B “3” NIACIN
What happens if our Vitamin B 3 is deificient in porphyria?
"In niacin (B3) deficiency the Gastrointestinal manifestations
include glossitis, cheilosis, stomatitis, nausea,
vomiting, and diarrhea. If untreated death occurs."
SOURCE:
Advanced Nutrition and Human Metabolism
J. Groff (251)
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Time released nicin therapy can be used in porphyria patients to reduce high
cholesterol.
SOURCE:
Robert Johnson M.D.
Internl Medicine
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VITAMIN B “12” COBALAMIN
What is Vitamin B-12?
Vitamin B 12 is the common name for Cobalamin.
SOURCE:
Sheryl Wilson MSN RD
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Vitamin B-12 iw important for metabolism.
Vitamin B-12 helps maintain healthy nerve cells, red blood cells, and is needed
to make DNA.
SOURCE:
Robert JOhnson M.D.
Internal Medicine
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Vitamin B-12is found in animal foods including shellfish, milk and milk products,
eggs, meat and poultry.
SOURCE:
John McIntosh
Nutrition Report
Remedy Winter 2002
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Where is Vitamin B-12 found?
Milk and other dairy products are good sources of Vitamin B-12.
SOURCE:
Sheryl Wilson MSN RD
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Vitamin B-12is found in animal foods including shellfish, milk and milk products,
eggs, meat and poultry.
SOURCE:
John McIntosh
Nutrition Report
Remedy Winter 2002
+++++++++++++++++++++++++++
What is the RDA for Vitamin B-12?
For men the RDA for Vitamin B-12 is 2.4 mcq daily.
For women the RDA for Vitamin B-12 is also 1.4 mcq daily.
SOURCE:
John McIntosh
Nutrition Report
Remedy Winter 2002
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